For the weekly shuffle maps, which can be quite fun,especially C&K varients. Avoid doing 6 players. 6 players often leads to map saturation i.e. not enough room (for the provided maps) and very long wait times to find a room and higher likelihood of players leaving mid game.
I’ve seen 2-3 players as the best but 4 can also work. But please avoid 6 players (and 5 for that matter).